What is quality control of crude drug?
The quality control of phytopharmaceuticals may be defined as the status of a drug, which is determined either by identity, purity, content, and other chemical, physical or biological properties, or by the manufacturing process. Quality control is based on three important pharmacopeial definitions:
What are the factors affecting the quality of crude drugs?
Crude drugs are collected from wild or cultivated plants and hence the proper selection of the plant parts and their proper collection give the improved quality of the plants….Environmental Factors:
- Collection season:
- Collection time:
- Age of the Plant:
What are the different steps in the preparation of crude drugs?
Following methods are used:
- Cutting: These are the parts of the plant (stem, root or leaf) which, if grown under suitable’ conditions, develop new plants.
- Layering: Roots are induced on the stem while it is still attached to the parent plant.
- Grafting:
- Micro propagation:
What are the different methods of evaluation of crude drugs?
Evaluation Of Crude Drugs.
- Organoleptic evaluation.
- Microscopic evaluation.
- Chemical evaluation.
- Physical evaluation.
- Biological evaluation.
Which parameter is not used in quality control of crude drug?
One of the following parameter is not used in quality control of crude drugs alcohol insoluble extractive . 7.
What is drug standardization?
Standardization of drugs means confirmation of its identity and determination of its quality and purity. The quality control standards of various medicinal plants, used in indigenous system of medicine, are significant nowadays in view of commercialization of formulations based on medicinal plants.
How do you store crude drugs?
The costly phytopharmaceuticals are required to be preserved at refrigerated temperature in well closed containers. Small quantities of crude drugs could be readily stored in air-tight, moisture proof and light proof containers such as tin, cans, covered metal tins, or amber glass containers.
What is classification of crude drug?
In this classification the crude drugs are classified according to kingdom, subkingdom, division, class, order, family, genus and species as follows. Class: Angiospermae (Angiosperms) are plants that produce flowers and Gymnospermae (Gymnosperms) which don’t produce flowers.
Why is moisture removed in crude drugs?
Drying consists of removal of suffi-cient moisture content of crude drug, so as to improve its quality and make it resistant to the growth of microorgan-isms. Drying inhibits partially enzymatic reactions. Drying also facilitates pulverizing or grinding of a crude drug.
What is crude drugs classification?
Classification of crude Drugs. • Crude drug i.e. Simple drug. • Crude drugs are plant, animal or their parts which after collection are subjected only to drying or making them into transverse/ longitudinal slices pieces or peeling them in some cases. They exist in natural form.
What is quality control parameter?
Depending on the downstream application, four main quality parameters can characterize the quality of your nucleic acid samples – quantity, purity, size and sequence. Variations in these parameters can impact your experiments and affect the data quality and results interpretation.
Why do we calculate ash value?
Ash values are helpful to determine the quality as well as purity of a crude drug, especially when the drug is present in powdered form. The object of ashing crude drugs is to remove the traces of organic matter which may be interferes in an analytical determination.
What is physical evaluation of crude drugs?
In crude plant evaluation, physical methods are often used to determine the solubility, specific gravity, optical rotation, viscosity, refractive index, melting point, water content, degree of fibre elasticity, and other physical characteristics of the herb material.
Why is drug standardization important?
Lack of quality control can affect the efficacy and safety of drugs that may lead to health problems in the consumers. Standardization of drugs is needed to overcome the problems of adulteration and is most developing field of research now.
What is the difference between crude drug and drug?
Crude drugs are plant or animal drugs that contain natural substances that have undergone only the processes of collection and drying. The term natural substances refers to those substances found in nature that have not had man-made changes made in their molecular structure.
What are the sources of crude drugs?
Source of crude drugs are plant (senna, opium, digitalis and Clove), Animal (Musk, Honey, Shark liver Oil) and Mineral (Shilajit, Talc, Bentonite). ➢ Significant number of synthetic drugs obtained from natural precursors.