What are the toxic effects of phenytoin?
The neurotoxic effects are concentration dependent and can range from mild nystagmus to ataxia, slurred speech, vomiting, lethargy and eventually coma and death. Paradoxically, at very high concentrations, phenytoin can lead to seizures.
Does phenytoin come in a suspension?
Phenytoin Oral Suspension, USP is a prescription medicine used to treat tonic-clonic (grand mal), complex partial (psychomotor or temporal lobe) seizures, and to prevent and treat seizures that happen during or after brain surgery.
What are the adverse effects of phenytoin and why explain?
Headache, nausea, vomiting, constipation, dizziness, feeling of spinning, drowsiness, trouble sleeping, or nervousness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Phenytoin may cause swelling and bleeding of the gums.
How is phenytoin oral suspension administered?
Swallow the tablet whole or chew it thoroughly before swallowing it together with a glass of water. Measure the oral suspension with a marked measuring spoon, oral syringe, or medicine cup. Rinse the dosing spoon or cup with water after each use.
Should you shake phenytoin?
Shake this medication well before each dose. Take this medication by mouth usually 2 or 3 times a day, or as directed by your doctor. This product is not recommended for use once a day. You may take it with food if stomach upset occurs.
Does phenytoin cause memory loss?
All drugs that depress signaling in the CNS can cause memory loss. Alternatives: Many patients with seizures do well on phenytoin (Dilantin), which has little if any impact on memory. Many patients with chronic nerve pain find that venlafaxine (Effexor) — which also spares memory — alleviates their pain.
What is the major concern after administering phenytoin to a patient with seizure?
Nervous System: The most common adverse reactions encountered with phenytoin therapy are nervous system reactions and are usually dose-related. Reactions include nystagmus, ataxia, slurred speech, decreased coordination, somnolence, and mental confusion.
Is phenytoin safe for child?
Phenytoin may make your child dizzy, drowsy, or less alert than normal, especially at the beginning of therapy. Have your child avoid tasks or activities that require alertness until you see how phenytoin affects them. Tell your child’s teacher that they are taking this medication.
Should phenytoin be taken on an empty stomach?
You may give phenytoin with food or milk, but be consistent. Always give phenytoin with food or milk or always give it on an empty stomach. If your child is taking chewable tablets, encourage your child not to swallow them whole.
How does phenytoin stop seizures?
Phenytoin is an anti-epileptic drug, also called an anticonvulsant. Phenytoin works by slowing down impulses in the brain that cause seizures. Phenytoin is used to control seizures. It does not treat all types of seizures, and your doctor will determine if it is the right medicine for you.
How do you give a child phenytoin?
You may give phenytoin with food or milk, but be consistent. Always give phenytoin with food or milk or always give it on an empty stomach. If your child is taking chewable tablets, encourage your child not to swallow them whole. Instead, the chewable tablets may be chewed, crushed, or mixed with food.
What are phenylalanine side effects?
– It is shown to have drug interaction effects. – Patients with schizophrenia, hyperthyroidism and cancer should take doctor’s approval before taking phenylalanine supplement. – Intake of high dosage increases the risks for behavioral and mental problems. – Overdose of phenylalanine results in toxicity symptoms, and may result in nervous breakdown.
Does phenytoin cause drowsiness?
Phenytoin oral capsule may cause drowsiness. This can slow your thinking and motor skills. You shouldn’t drive, use machinery, or do other tasks that require alertness until you know how this
Can phenytoin cause cancer?
Phenytoin has been causally implicated in three human cancers: lymphoma, myeloma and neuroblastoma, the latter specifically in the setting of foetal hydantoin syndrome.
Can phenytoin cause liver damage?
Phenytoin causes serum glucose ( sugar) to rise. Thus, blood sugar should be monitored closely when phenytoin is administered to patients with diabetes. Phenytoin can potentially injure the liver although this is an uncommon occurrence.