What are poly phenolic compounds?
Polyphenols are beneficial compounds in many plant foods that can be grouped into flavonoids, phenolic acid, polyphenolic amides, and other polyphenols. They may improve digestion, brain function, and blood sugar levels, as well as protect against blood clots, heart disease, and certain cancers.
What is the composition of phenolic?
Through HPLC analysis, we found 6 phenolic acids (gallic acid, p-coumaric acid, ferulic acid, sinapic acid, syringic acid, and p-anisic acid), and 12 flavonoids (catechin, epicatechin, rutin, naringin, myricetin, hesperidin, diosmin, narigenin, luteolin, hesperetin, kamempferol, and apigenin) in these extracts (Table 2 …
What are examples of useful phenolic compounds?
Plant phenolic compounds can act as antioxidants, structural polymers (lignin), attractants (flavonoids and carotenoids), UV screens (flavonoids), signal compounds (salicylic acid and flavonoids) and defense response chemicals (tannins and phytoalexins).
What is total phenolic compound?
Phenolic compounds are important plant constituents with redox properties responsible for antioxidant activity . The hydroxyl groups in plant extracts are responsible for facilitating free radical scavenging.
How many phenolic compounds are there?
More than 8000 phenolic compounds as naturally occurring substances from plants have been reported [1,2]. It is very interesting to note that half of these phenolic compounds are flavonoids presenting as aglycone, glycosides and methylated derivatives [1,2].
How is TPC value calculated?
Firstly, you need to calculate the result from the equation that you obtained for your standard curve (x is concentration of total polyphenols and y is absorbance reading). x = y/14.26. Total volume of your extract was 40 ml, so now you need to calculate the quantity of total polyphenols in it which equals 40x.
Is EGCG good for your skin?
EGCG reduced melanin secretion and production in melanoma cells. Together, these results suggest that EGCG might be used as a cosmetic ingredient with positive effects on skin hydration, moisture retention, and wrinkle formation, in addition to radical scavenging activity and reduction of melanin generation.
What is TPC assay?
Total phenolic content (TPC) assay using Folin-Ciocalteu method was used to assess the presence and level of phenolic compounds in each sample. The present study showed that both methanolic and ethanolic extracts of P. minus had the highest TPC and followed by M.
How do you calculate phenolic content?
The total phenolic content can be calculated as natural compound (gallic acid) equivalent (GAE) by the following equation: T= C XV/M .
Is EGCG safe?
EGCG supplements are considered safe for most people when taken at commonly used doses (300–400 mg/day) , but high doses (800–1600 mg of EGCG per day) may negatively affect liver function .
How is phenolic content measured?
What is total phenolic content principle?
The principle of the F–C assay is the reduction of the Folin–Ciocalteu reagent (FCR) in the presence of phenolics resulting in the production of molybdenum–tungsten blue that is measured spectrophotometrically at 760 nm and the intensity increases linearly with the concentration of phenolics in the reaction medium as …
What are the biological properties of phenolic compounds?
Phenolic compounds are known to exhibit various biological activities such as antimicrobial, antioxidant and anti-inflammatory properties. This book chapter begins with classification of phenolic compounds in concise manner followed by going through their chemical properties that are essential for their biological activities.
What is an example of a hydroxyl substituted phenol?
Simple substituted phenol compounds can be hydroxyphenols or dihydroxybenzenes. Examples are catechol (1,2-dihydroxybenzene), resorcinol (1,3-dihydroxybenzene), and hydroquinone (1,4-dihydroxybenzene) ( Figure 3 ). Figure 3. The structure of hydroxyl-substituted phenols.
Do phenolic compounds show intramolecular H-bonding?
Phenolic compound with adjacent hydroxyl groups such as protocathechuic acid, can exhibit intramolecular H-bonding ( Figure 29 ). Phenolic compounds with adjacent hydroxyl and alkoxy groups are also capable of intramolecular H-bonding. Figure 29. Intramolecular H-bonding of phenolic compounds.
Can phenolic compounds undergo oxidation reactions?
Phenolic compounds can undergo oxidation reactions. Homolytic (symmetrical) oxidative O-H bond cleavage gives rise to a phenolic radical ( Figure 34 ). Such radicals are stabilized by resonance by delocalization of the resultant single electron over the ring.