Can diabetes cause high AST and ALT levels?
Results. Participants with undiagnosed diabetes were more likely to have elevated ALT and AST levels (OR = 1.82, 95% CI 1.47, 2.42; OR = 1.99, 95% CI 1.46, 2.71, respectively).
Can type 2 diabetes cause elevated ALT?
In a well-defined population of newly diagnosed people with T2DM, there is a high incidence of abnormal ALT levels, which is associated with features of the metabolic syndrome (obesity and lipid abnormalities), but not glycemic control.
Does High ALT mean diabetes?
Researchers found that elevated levels of ALT and GGT (positive correlation) and the lowest levels of AST/ALT (negative correlation) are associated with a higher prevalence for type 2 diabetes and prediabetes. ALT levels seem to be the most predictive of type 2 diabetes in women.
What causes high liver enzymes in diabetes?
Glycogenic hepatopathy is a rare cause of high transaminase levels in type 1 diabetes mellitus. This condition, characterized by elevated liver enzymes and hepatomegaly, is caused by irreversible and excessive accumulation of glycogen in hepatocytes.
Does diabetes affect ALT?
A higher incidence of liver function test abnormalities has been associated with individuals with T2DM than individuals without T2DM [6]. In the present study, the ALT was elevated in 40.4% of the diabetic population, while the AST and ALP were increased only in 17% and 16% of the diabetic population, respectively.
Is ALT over 100 need for concern?
An ALT test result of >100 IU/l is a clear indicator of serious liver disease, but a mildly elevated ALT result (30–100 IU/l) is often ascribed to the use of medication (for example statins) or alcohol, obesity, or, for lower ALT levels (<50 IU/l), considered as part of the normal distribution of test results.
How do you treat high ALT levels?
For most causes of high ALT, treatment involves lifestyle changes, such as exercise, a modified diet, and reducing alcohol intake. Depending on the results of your liver panel and your medical history, your healthcare professional may recommend checking them again at a later date.
Can you bring ALT levels down?
People can lower their ALT levels by making lifestyle changes, such as taking regular exercise and changing their diet. Increasing fiber intake, reducing saturated fats and processed foods, as well as consuming a range of nutrients from fruits and vegetables may all help to lower levels.