What is Recormon?
Recormon (in some countries NeoRecormon) is a medicine that stimulates red-blood-cell growth. The active substance in Recormon, epoetin beta, is a copy of a human hormone called erythropoietin. Erythropoietin is produced by the kidneys and stimulates the production of red blood cells from the bone marrow.
What is the use of recormon?
Recormon is indicated for: Treatment of anemia associated with chronic renal failure (renal anemia) in patients on dialysis. Treatment of symptomatic renal anemia in patients not yet undergoing dialysis.
What is the generic name of recormon?
Drug Name : Erythropoietin Erythropoietin(Epogen) generic Neo Recormon (10000 iu) is a haematopoietic agent, prescribed for anemia in people with chronic kidney failure.
Why do dialysis patients need recormon?
In chronic renal failure patients an increase in heparin dose during hemodialysis is frequently required during the course of therapy with Recormon as a result of the increased packed cell volume.
What is the major difference between epoetin alfa and darbepoetin?
There are no clinically significant differences in the safety and efficacy of epoetin alfa (Epogen, Procrit) and darbepoetin alfa (Aranesp), the two drugs most commonly used to treat anemia in cancer patients undergoing chemotherapy or radiation treatments, according to a new report by the Agency for Healthcare …
What is erythropoietin injection?
Epoetin injection is a man-made version of human erythropoietin (EPO). EPO is produced naturally in the body, mostly by the kidneys. It stimulates the bone marrow to produce red blood cells. If the body does not produce enough EPO, severe anemia can occur.
Why does CKD cause anemia?
Anemia in people with CKD often has more than one cause. When your kidneys are damaged, they produce less erythropoietin (EPO), a hormone that signals your bone marrow—the spongy tissue inside most of your bones—to make red blood cells.
What is the difference between epoetin alfa and beta?
Epoetin beta was found to differ from epoetin alfa in containing: (a) a greater proportion of more basic isoforms, (b) a greater proportion of EPO binding to Erythrina cristagalli agglutinin (which binds N-glycans with nonsialylated outer Gal beta1-4GlcNAc moieties), and (c) isoforms with higher in-vivo:in-vitro …
What is the difference between darbepoetin and erythropoietin?
Erythropoietin is the name of a hormone produced mainly in the kidney, which takes part in the production of red blood cells. Epoetin and darbepoetin work in a similar way to this hormone to increase the number of red blood cells and treat anaemia.
What class of drug is erythropoietin?
Epoetin alfa products are in a class of medications called erythropoiesis-stimulating agents (ESAs). They work by causing the bone marrow (soft tissue inside the bones where blood is made) to make more red blood cells.
What is the role of erythropoietin?
Abstract. Erythropoietin (Epo), which is produced by the kidney in the adult and by the liver in the fetus, increases red blood cells by supporting the survival of erythroid progenitor cells and stimulating their differentiation and proliferation via binding to Epo receptor (EpoR).
What drugs are harmful to kidneys?
What Meds Might Hurt My Kidneys?
- Antibiotics.
- Diuretics.
- Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
- Proton Pump Inhibitors (PPIs)
- Supplements.
- Laxatives.
- If You Have Kidney Disease, Other Medications Can Be Harmful.
Which is better erythropoietin alpha or beta?
Conclusion. In our assessment of hemodialysis patients, erythropoietin beta was found more effective than erythropoietin alpha.
What is the primary difference between epoetin and darbepoetin?
In the United States, epoetin alfa (EPO) is the predominant ESA used by large dialysis chains, whereas the more recently approved longer-acting ESA, darbepoetin alfa (DPO), is mainly used in independent and hospital-based dialysis units. In 2011, 94.1% of ESA-treated US hemodialysis patients used EPO and 5.9% used DPO.