Does topiramate help with bipolar disorder?
Topiramate is most useful for people who have bipolar mood disorders that other mood stabilizers have been unable to control. It can relieve symptoms and make taking antidepressants possible for people who ere unable to take them before without experiencing mania or a mixed state.
Can Topamax worsen depression?
Anticonvulsants like Topamax, can also profoundly affect mood, contributing to mental illnesses like anxiety, depression, or mania. Topamax can have several neurocognitive and neuropsychiatric side effects, including this case of Topamax-induced dissociative disorder.
How long does it take for Topamax to work for bipolar?
treated 20 patients with bipolar I disorder or schizoaffective disorder with adjunctive topiramate (mean dose = 210.5 mg/day) over a 5-week period. Twelve patients (60%) responded to topiramate, and the time to response ranged from 2 to 4 weeks.
How much Topamax should I take for bipolar?
Rapid-cycling bipolar disorders Topiramate was introduced at a dose of 25 mg/day, and increased by 25 mg/day every 5–7 days until clinical response or tolerability was reached. The dose range was 100–150 mg/day.
Can Topamax make you manic?
In addition, topiramate has been reported to cause mood swings in 1%–3% of the subjects. Topiramate may induce manic episodes in patients with a history of seizures or prior psychiatric illnesses.
Is Topamax good for mania?
Conclusions: Topiramate appears to have efficacy for the manic and mixed phases of bipolar illness. Other preliminary data suggest antidepressant efficacy too. Among obese bipolar subjects, the weight loss potential of topiramate may be beneficial.
Does Topamax depression go away?
The bottom line. Topamax isn’t approved to treat depression or bipolar disorder with depression, but it may be helpful for people who have not found relief with other mood-stabilizing drugs. For this reason, a doctor may decide, after careful evaluation, to prescribe Topamax off label for treating depression.
Can Topamax cause personality change?
Topamax can sometimes cause personality changes that affect the way people behave, react, feel, or interact with others. For example, the drug may cause agitation, aggression, or other behavior problems. Topamax may also cause mood changes, such as anxiety, mood swings, and depression.
Does Topamax make you feel happy?
The study found that the participants taking Topamax in addition to their prescribed depression medication significantly improved depressed mood, suicidality, insomnia, agitation, and anxiety symptoms compared to those taking a placebo.
Does Topamax cause psychosis?
The incidence of psychosis during clinical trials of topiramate was 0.8%, not significantly different from the rate for placebo or reported rates of psychosis in patients with refractory epilepsy. We observed psychotic symptoms in five patients soon after initiation of topiramate therapy.
Is Topamax a mood stabilizer?
Topiramate is a novel anticonvulsant agent with a broad spectrum mechanism of action, and recent clinical reports indicate that it may have mood stabilizing properties in bipolar disorder.
Does Topamax make you dumb?
Topamax can have significant side effects, most notably difficulties with memory, attention and concentration. Some doctors jokingly call the drug ”Dopeamax,” and say it can make patients ”skinny and stupid. ”
Can Topamax change your personality?
Can topiramate make you manic?
Topiramate may induce manic episodes in patients with a history of seizures or prior psychiatric illnesses. In the case reported by Jochum, an alteration in AMPA neurotransmission was considered to be the cause of topiramate-associated manic episode.
Does Topamax calm you down?
Topamax may also cause mood changes, such as anxiety, mood swings, and depression. In addition, the medication may raise your risk for suicidal thoughts or behaviors. All antiepileptic drugs (medications used to treat seizures due to epilepsy) are known to slightly raise the risk of suicidal thoughts and behaviors.
How does Topamax help bipolar?
Does Topamax help with bipolar? Several studies have demonstrated the efficacy of topiramate in the treatment of bipolar disorder, including refractory populations, and in the treatment of posttraumatic stress disorder. Topiramate led to substantial weight loss in patients with bipolar disorders in these studies.
What medication is best for bipolar depression?
Today, mood-stabilizing drugs are a mainstay treatment for bipolar disorder. Doctors may prescribe lithium, an antimanic drug, or an antipsychotic drug—or a combination of both—to alleviate symptoms of depression without triggering a manic episode.
What not to take with topiramate?
feeling sick – stick to simple meals and do not eat rich or spicy food. It might help to take your topiramate after a meal or snack. feeling sleepy, dizzy or tired – do not drive or use tools or machinery. Try to avoid drinking alcohol, as this will make you feel more tired.
What is Topamax used to treat?
alcoholism