Is Arimidex similar to tamoxifen?
Arimidex and tamoxifen belong to different drug classes. Arimidex is a nonsteroidal aromatase inhibitor and tamoxifen is a nonsteroidal antiestrogen. Brand names for tamoxifen include Nolvadex and Soltamox, Nolvadex.
Is tamoxifen as effective as anastrozole?
RESULTS: Anastrozole was as effective as tamoxifen in terms of OR (21% v 17% of patients, respectively), with clinical benefit (CR + PR + stabilization ≥ 24 weeks) observed in 59% of patients on anastrozole and 46% on tamoxifen (two-sided P = . 0098, retrospective analysis).
How much better are aromatase inhibitors than tamoxifen?
Aromatase inhibitors, drugs which block oestrogen production, are even more effective than tamoxifen in postmenopausal women, reducing this risk by a further 30%.
Which is safer Arimidex or tamoxifen?
Arimidex Still Better Than Tamoxifen After Surgery to Reduce Recurrence Risk. After 10 years of follow-up, research shows that 5 years of Arimidex is better at reducing the risk of hormone-receptor-positive breast cancer recurrence than 5 years of tamoxifen.
Which is better tamoxifen or Arimidex?
After 10 years of follow-up, a study shows that taking Arimidex for 5 years is better at reducing the risk of hormone-receptor-positive breast cancer recurrence than taking tamoxifen for 5 years. These results were presented at the 2010 American Society of Clinical Oncology (ASCO) Breast Cancer Symposium.
Which has less side effects tamoxifen or Arimidex?
The latest ATAC analysis also found that the overall risk of side effects (both serious and not-so-serious) was lower for Arimidex compared to tamoxifen. Earlier ATAC results showed that serious side effects were less common in women taking Arimidex compared to women taking tamoxifen.
Which is better aromatase inhibitor or tamoxifen?
For women with early-stage oestrogen receptor (ER)-positive breast cancer, adjuvant tamoxifen reduces 15-year breast cancer mortality by a third. Aromatase inhibitors are more effective than tamoxifen in postmenopausal women but are ineffective in premenopausal women when used without ovarian suppression.
Why does anastrozole cause joint pain?
Women taking a type of hormone therapy called aromatase inhibitors (such as anastrozole, letrozole and exemestane) for breast cancer, may have joint pain and sometimes muscle pain. This is probably caused by a decrease in oestrogen levels. Joint pain is also a common symptom of the menopause.
What are the long term side effects of Arimidex?
Examples of the long-term side effects of Arimidex include:
- osteoporosis (bone weakness) or bone fractures.
- depression.
- increased cholesterol levels.
- liver problems.
- hair loss or hair thinning.
When should I switch from tamoxifen to aromatase inhibitors?
Most women should take adjuvant hormonal therapy for a total of 5 years. Options include: taking the same hormonal therapy for all 5 years (monotherapy) taking tamoxifen for 2 or 3 years and then switching to an aromatase inhibitor until hormonal therapy has been taken for a total of 5 years (sequential therapy)
Is Arimidex hard on the liver?
The majority of people who reported liver problems with Arimidex didn’t experience any symptoms. In most cases, the only change noted is a slight increase in liver enzymes. However, in very rare instances, more severe problems such as hepatitis can occur.
How much does Arimidex increase survival?
High cholesterol levels. Arimidex may increase your cholesterol levels.
How much is tamoxifen without insurance?
The lowest GoodRx price for the most common version of tamoxifen is around $38.09, 79% off the average retail price of $184.18. A Savings Club is a program with a required monthly or annual fee that gives you access to special pricing.
How expensive is tamoxifen?
hot flashes
What is an indication for taking tamoxifen?
If you have an allergy to tamoxifen or any other part of this medicine (tamoxifen tablets).